James VI/I king of Scotland

mardi 25 septembre 2018

James VI/I king of Scotland

(19 June 1566 – 27 March 1625) was King of Scotland as James VI, and King of England and King of Ireland as James I. He was the first monarch to be called the king of Great Britain. He ruled in Scotland as James VI from 24 July 1567 until his death and he ruled in England and Ireland from 24 March 1603 until his death.
After about the age of fifty, James suffered increasingly from arthritis, gout and kidney stones. He also lost his teeth and drank heavily. The King was often seriously ill during the last year of his life, leaving him an increasingly peripheral figure, rarely able to visit London, while Buckingham consolidated his control of Charles to ensure his own future. One theory is that James may have suffered from porphyria, a disease of which his descendant George III of the United Kingdom exhibited some symptoms. James described his urine to physician Théodore de Mayerne as being the "dark red colour of Alicante wine". The theory is dismissed by some experts, particularly in James's case, because he had kidney stones which can lead to blood in the urine, colouring it red.
In early 1625, James was plagued by severe attacks of arthritis, gout, and fainting fits, and fell seriously ill in March with tertian ague and then suffered a stroke. He died at Theobalds House on 27 March during a violent attack of dysentery, with Buckingham at his bedside.

It has been claimed that King James VI/I, an antecedent of King George III, suffered from acute porphyria, and that the disease was passed on to George III through his grand-daughter Sophie, mother of George I. The life of James is reviewed and previously-proposed diagnoses are considered. James’s medical history is discussed in detail and, where possible, examined with validated symptom scales. Using an online database of neurological diseases, the authors show that James’s symptomatology is compatible with a diagnosis of Attenuated (mild) Lesch-Nyhan disease; no evidence was found to support a diagnosis of acute porphyria. In addition, there is evidence of associated Asperger traits which may explain some of the King’s unusual behavioural and psycho-social features. [The nature of King James VI/I’s medical conditions: new approaches to the diagnosis Timothy Peters, Peter Garrard, Vijeya Ganesan, History of Psychiatry 23(3):277-290 · January 2012]